98.5% PureGrowth HormoneView on PubChem
Tesamorelin 10mg
A synthetic growth hormone-releasing hormone (GHRH) analog, Tesamorelin is an essential research tool for investigating pituitary function, GH secretion dynamics, and somatotropic axis regulation.
Molecular Weight
5135.89 g/mol
Sequence
44-amino acid sequence (GHRH analog)
$179.99
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Molecular Formula
C221H366N72O67S
Molecular Weight
5135.89 g/mol
Purity
98.5%
CAS Number
218949-48-5
Half Life
26-38 minutes
Storage
-20°C
Administration
subcutaneous
Research Status
approved
Description
Tesamorelin is a stabilized analog of human growth hormone-releasing hormone (GHRH) consisting of the complete 44-amino acid sequence with an added trans-3-hexenoic acid modification. This structural enhancement significantly increases the compound's stability and half-life, making it highly suitable for both acute and chronic research protocols investigating the somatotropic axis.
Research suggests Tesamorelin selectively stimulates pituitary somatotroph cells to synthesize and release endogenous growth hormone in a physiologically pulsatile manner. This makes it an invaluable tool for studies examining GH secretion dynamics, IGF-1 pathway activation, and body composition changes—particularly visceral adipose tissue regulation.
Research Applications
Growth hormone secretion studies
IGF-1 pathway research
Body composition investigations
Visceral adipose tissue studies
Pituitary function research
For scientific research purposes only. Not for human consumption.
Research
FDA-approved for:
- HIV-associated lipodystrophy
- Visceral adipose reduction
- Cognitive function (research)
- NAFLD/NASH treatment
- Cardiovascular health
- Muscle preservation
- Bone density
- Quality of life improvement
Mechanism
Synthetic GHRH analog:
1. Binds to GHRH receptors
2. Stimulates pituitary GH release
3. Increases IGF-1 production
4. Preserves physiological pulsatility
5. Reduces visceral fat specifically
6. Maintains feedback mechanisms
7. Minimal effect on glucose
Benefits
Reduced visceral adipose tissue
Improved body composition
Maintained muscle mass
Better lipid profiles
Improved cognitive function
Enhanced quality of life
Cardiovascular benefits
Preserved bone density
Dosage
FDA-approved dosing:
- Standard: 2mg daily subcutaneously
- Administration: Inject into abdomen
- Timing: Bedtime preferred
- Duration: Continuous use
- Monitor IGF-1 levels regularly
Safety
Common side effects:
- Injection site reactions (most common)
- Joint pain
- Muscle pain
- Swelling/edema
- Paresthesia
- Rash
- Hyperglycemia (monitor)
- IGF-1 elevation
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