98.5% PureGrowth HormoneView on PubChem
CJC-1295 5mg
A synthetic analog of growth hormone-releasing hormone (GHRH) with enhanced plasma stability, CJC-1295 is widely utilized in endocrinology research exploring pulsatile GH secretion patterns.
Molecular Weight
3649.30 g/mol
Sequence
Tyr-D-Ala-Asp-Ala-Ile-Phe-Thr-Gln-Ser-Tyr-Arg-Lys-Val-Leu-Ala-Gln-Leu-Ser-Ala-Arg-Lys-Leu-Leu-Gln-Asp-Ile-Leu-Ser-Arg-NH2
$129.99
1
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Molecular Formula
C165H271N47O46
Molecular Weight
3649.30 g/mol
Purity
98.5%
CAS Number
863288-34-0
Half Life
6-8 days (with DAC), 30 minutes (without DAC)
Storage
-20°C
Administration
subcutaneous
Research Status
phase2
Description
CJC-1295 is a tetrasubstituted 30-amino acid peptide analog of growth hormone-releasing hormone (GHRH 1-29). Through strategic amino acid modifications, this compound exhibits significantly extended biological half-life compared to native GHRH, making it an invaluable tool for researchers studying sustained growth hormone axis modulation in laboratory settings.
Research literature suggests that CJC-1295 interacts with GHRH receptors in pituitary tissue, potentially influencing growth hormone secretion patterns. Scientific studies have examined its effects on IGF-1 expression, body composition parameters, and metabolic markers in various animal models.
Research Applications
Endocrine system studies
Growth hormone secretagogue research
Metabolic investigations
Body composition analysis
Pituitary function research
For laboratory and scientific research purposes only.
Research
CJC-1295 is a synthetic GHRH analog studied for:
- Growth hormone deficiency treatment
- Age-related hormone decline
- Body composition improvement
- Muscle growth and recovery
- Fat loss research
- Sleep quality improvement
- Cognitive function enhancement
- Anti-aging research
Mechanism
CJC-1295 functions by:
1. Binding to GHRH receptors on pituitary somatotrophs
2. Stimulating cAMP production
3. Triggering growth hormone release
4. Extended half-life through DAC technology
5. Preserving natural GH pulsatile secretion
6. Enhancing IGF-1 production
7. Negative feedback loop preservation
Benefits
Increased growth hormone production
Enhanced IGF-1 levels
Improved body composition
Increased muscle mass
Reduced body fat
Better sleep quality
Enhanced recovery
Improved skin elasticity
Increased bone density
Dosage
Research protocols typically use:
- With DAC: 1-2mg once or twice weekly
- Without DAC: 100-200mcg daily
- Timing: Evening administration preferred
- Cycle: 8-12 weeks on, 4 weeks off
- Best taken on empty stomach
Safety
Potential side effects include:
- Injection site reactions
- Temporary fatigue
- Headaches
- Dizziness
- Flushing
- Vivid dreams
- Temporary hypoglycemia
- Water retention (mild)
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