99% PureAnti-AgingView on PubChem
NAD+ 500mg
The essential oxidized form of nicotinamide adenine dinucleotide, NAD+ serves as a critical coenzyme in cellular metabolism research and is central to studies on aging, DNA repair, and energy production.
Molecular Weight
663.43 g/mol
Sequence
Not applicable - small molecule
$199.99
1
Lab Tested
99%+ Purity
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Molecular Formula
C21H27N7O14P2
Molecular Weight
663.43 g/mol
Purity
99%
CAS Number
53-84-9
Half Life
1-2 hours
Storage
-20°C
Administration
intravenous
Research Status
approved
Description
NAD+ (Nicotinamide Adenine Dinucleotide, oxidized form) is a vital coenzyme present in all living cells, functioning as a critical electron carrier in metabolic redox reactions. As both a substrate for important enzyme families including sirtuins and PARPs, and a key component of cellular energy metabolism, NAD+ has become one of the most intensively studied molecules in contemporary biological research.
Scientific studies have documented NAD+ involvement in over 500 enzymatic reactions, spanning glycolysis, the citric acid cycle, and oxidative phosphorylation. Research suggests that NAD+ levels may influence sirtuin activity, DNA repair mechanisms, circadian rhythm regulation, and mitochondrial function.
Research Applications
Cellular metabolism studies
Sirtuin pathway research
DNA repair mechanisms
Mitochondrial function investigations
Aging and longevity research
High-purity grade for in vitro and laboratory research applications.
Research
NAD+ research encompasses:
- Aging and longevity
- Cellular energy metabolism
- DNA repair mechanisms
- Neuroprotection
- Cardiovascular health
- Metabolic disorders
- Addiction treatment
- Chronic fatigue syndrome
Mechanism
NAD+ is essential for:
1. Cellular respiration and ATP production
2. Sirtuin enzyme activation
3. PARP enzyme function for DNA repair
4. Calcium signaling regulation
5. Circadian rhythm control
6. Mitochondrial function
7. Gene expression regulation
Benefits
Increased cellular energy
Enhanced DNA repair
Improved cognitive function
Better metabolic health
Anti-aging effects
Neuroprotection
Improved muscle function
Enhanced endurance
Better sleep quality
Dosage
Research protocols:
- IV infusion: 250-1000mg over 1-4 hours
- Frequency: 1-2 times weekly
- Loading: Daily for 5-10 days
- Maintenance: Weekly or bi-weekly
- Combine with precursors for best results
Safety
Generally safe but may cause:
- Flushing
- Nausea
- Headaches
- Fatigue
- Dizziness
- Cramping (during infusion)
- Chest tightness (rare)
- Anxiety (high doses)
