98.7% PureAnti-AgingView on PubChem
MOTS-C 10mg
A 16-amino acid peptide encoded within the mitochondrial genome, MOTS-c represents a groundbreaking class of mitochondrial-derived peptides with significant implications for metabolic and longevity research.
Molecular Weight
2174.64 g/mol
Sequence
MRWQEMGYIFYPRKLR
$149.99
1
Lab Tested
99%+ Purity
Fast Shipping
Molecular Formula
C101H152N28O22S2
Molecular Weight
2174.64 g/mol
Purity
98.7%
CAS Number
1627580-64-6
Half Life
4 hours (plasma), 12-24 hours (cellular)
Storage
-80°C
Administration
subcutaneous
Research Status
preclinical
Description
MOTS-c (Mitochondrial Open reading frame of the Twelve S rRNA type-c) is a 16-amino acid peptide encoded by a short open reading frame within the mitochondrial 12S rRNA gene. This discovery represented a paradigm shift in understanding mitochondrial biology, revealing that mitochondria actively produce signaling peptides that may influence cellular metabolism.
Research indicates that MOTS-c may influence AMPK activation, glucose metabolism, and cellular stress responses. Published studies have examined its effects on insulin sensitivity markers, exercise-related metabolic adaptations, and age-associated metabolic changes in various research models.
Research Applications
Mitochondrial biology
Metabolic research
AMPK pathway studies
Aging and longevity investigations
Exercise physiology research
Strictly for laboratory research and scientific investigation.
Research
MOTS-c research areas:
- Metabolic regulation
- Insulin sensitivity
- Exercise performance
- Age-related metabolic decline
- Mitochondrial function
- Obesity and diabetes
- Cellular stress response
- Longevity research
Mechanism
MOTS-c functions through:
1. AMPK pathway activation
2. Improved glucose utilization
3. Enhanced fatty acid oxidation
4. Mitochondrial biogenesis stimulation
5. Cellular stress response activation
6. Metabolic homeostasis regulation
7. Nuclear translocation under stress
Benefits
Improved insulin sensitivity
Enhanced fat metabolism
Increased exercise capacity
Better glucose control
Mitochondrial health
Reduced inflammation
Potential longevity benefits
Metabolic flexibility
Weight management support
Dosage
Research dosing:
- Metabolic: 5-10mg weekly
- Exercise performance: 10mg before training
- Age-related decline: 5mg twice weekly
- Maximum: 15mg weekly
- Cycle: 4-8 weeks on, 4 weeks off
Safety
Limited side effect data:
- Injection site reactions
- Temporary fatigue
- Mild nausea
- Transient hypoglycemia
- Generally well-tolerated
- Long-term effects unknown
