MOTS-C 10mg98.7% Pure
Anti-Aging

MOTS-C 10mg

A 16-amino acid peptide encoded within the mitochondrial genome, MOTS-c represents a groundbreaking class of mitochondrial-derived peptides with significant implications for metabolic and longevity research.

Molecular Weight

2174.64 g/mol

Sequence

MRWQEMGYIFYPRKLR

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Molecular Formula

C101H152N28O22S2

Molecular Weight

2174.64 g/mol

Purity

98.7%

CAS Number

1627580-64-6

Half Life

4 hours (plasma), 12-24 hours (cellular)

Storage

-80°C

Administration

subcutaneous

Research Status

preclinical

View on PubChem

Description

MOTS-c (Mitochondrial Open reading frame of the Twelve S rRNA type-c) is a 16-amino acid peptide encoded by a short open reading frame within the mitochondrial 12S rRNA gene. This discovery represented a paradigm shift in understanding mitochondrial biology, revealing that mitochondria actively produce signaling peptides that may influence cellular metabolism. Research indicates that MOTS-c may influence AMPK activation, glucose metabolism, and cellular stress responses. Published studies have examined its effects on insulin sensitivity markers, exercise-related metabolic adaptations, and age-associated metabolic changes in various research models. Research Applications Mitochondrial biology Metabolic research AMPK pathway studies Aging and longevity investigations Exercise physiology research Strictly for laboratory research and scientific investigation.

Research

MOTS-c research areas: - Metabolic regulation - Insulin sensitivity - Exercise performance - Age-related metabolic decline - Mitochondrial function - Obesity and diabetes - Cellular stress response - Longevity research

Mechanism

MOTS-c functions through: 1. AMPK pathway activation 2. Improved glucose utilization 3. Enhanced fatty acid oxidation 4. Mitochondrial biogenesis stimulation 5. Cellular stress response activation 6. Metabolic homeostasis regulation 7. Nuclear translocation under stress

Benefits

Improved insulin sensitivity Enhanced fat metabolism Increased exercise capacity Better glucose control Mitochondrial health Reduced inflammation Potential longevity benefits Metabolic flexibility Weight management support

Dosage

Research dosing: - Metabolic: 5-10mg weekly - Exercise performance: 10mg before training - Age-related decline: 5mg twice weekly - Maximum: 15mg weekly - Cycle: 4-8 weeks on, 4 weeks off

Safety

Limited side effect data: - Injection site reactions - Temporary fatigue - Mild nausea - Transient hypoglycemia - Generally well-tolerated - Long-term effects unknown
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