98.8% PureTanning PeptidesView on PubChem
Melanotan II 10mg
A synthetic cyclic heptapeptide analog of alpha-melanocyte stimulating hormone, Melanotan II is utilized in melanocortin receptor research spanning pigmentation, metabolic, and behavioral studies.
Molecular Weight
1024.18 g/mol
Sequence
Ac-Nle-cyclo[Asp-His-D-Phe-Arg-Trp-Lys]-NH2
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Molecular Formula
C50H69N15O9
Molecular Weight
1024.18 g/mol
Purity
98.8%
CAS Number
121062-08-6
Half Life
33 hours
Storage
-20°C
Administration
subcutaneous
Research Status
phase3
Description
Melanotan II (MT-II) is a synthetic cyclic lactam analog of alpha-melanocyte-stimulating hormone (α-MSH). This heptapeptide demonstrates affinity for multiple melanocortin receptors (MC1R through MC5R), making it a versatile research tool for investigating the complex melanocortin system. Its cyclized structure provides enhanced stability for laboratory applications compared to linear peptide analogs. Scientific literature documents extensive research into Melanotan II's interactions with melanocortin pathways. Studies have examined its effects on melanogenesis, feeding behavior in animal models, and various metabolic parameters. The compound's broad receptor activity profile has generated research interest across multiple disciplines. Research Applications Melanocortin receptor studies Pigmentation research Metabolic pathway investigations Appetite regulation studies Skin biology research For qualified researchers and laboratory use only. Not for human use.
Research
Melanotan II research includes:
- Melanogenesis and tanning
- Sexual dysfunction treatment
- Appetite suppression
- Autism spectrum behaviors
- Addiction and impulse control
- Inflammatory conditions
- Cardiovascular protection
- Metabolic syndrome
Mechanism
MT-II is a melanocortin receptor agonist:
1. Binds to MC1R triggering melanogenesis
2. MC3R and MC4R activation for appetite control
3. MC4R activation for sexual arousal
4. Central nervous system effects
5. Peripheral anti-inflammatory actions
6. Metabolic rate enhancement
7. Cardiovascular effects via MC receptors
Benefits
Enhanced tanning without UV exposure
Improved sexual function
Appetite suppression
Fat loss
Increased energy
Anti-inflammatory effects
Potential neuroprotection
Improved insulin sensitivity
Dosage
Research protocols:
- Loading: 0.25-0.5mg daily for 7-10 days
- Maintenance: 0.5-1mg once or twice weekly
- Sexual function: 0.5-2mg as needed
- Start low to assess tolerance
- Best taken before bedtime to minimize nausea
Safety
Common side effects include:
- Nausea (especially initial doses)
- Facial flushing
- Decreased appetite
- Spontaneous erections (males)
- Fatigue
- Increased blood pressure
- Darkening of moles/freckles
- Yawning and stretching